Holin dehidrogenaza
(preusmereno sa Holinska dehidrogenaza)
| Holin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.99.1 | ||||||||
| CAS broj | 9028-67-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Holin dehidrogenaza (EC 1.1.99.1, holinska oksidaza, holin-citohromna c reduktaza, holin:(akceptor) oksidoreduktaza, holin:(akceptor) 1-oksidoreduktaza) je enzim sa sistematskim imenom holin:akceptor 1-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- holin + akceptor betain aldehid + redukovani akceptor
Ovaj enzim je hinoprotein. Kod mnogih bakterija, biljki i životinja, osmoprotektant betain se sintetiše koristeći različite enzime koji katalizuju konverziju: (1) holina u betain aldehid i (2) betain aldehida u betain.
Reference
[uredi | uredi izvor]- ^ Ameyama, M., Shinagawa, E., Matsuchita, K., Takimoto, K., Nakashima, K. and Adachi, O. (1985). „Mammalian choline dehydrogenase is a quinoprotein”. Agric. Biol. Chem. 49: 3623—3626.
- ^ Ebisuzaki, K. & Williams, J.N. (1955). „Preparation and partial purification of soluble choline dehydrogenase from liver mitochondria”. Biochem. J. 60: 644—646. PMID 13249959.
- ^ Gadda, G. & McAllister-Wilkins, E.E. (2003). „Cloning, expression, and purification of choline dehydrogenase from the moderate halophile Halomonas elongata”. Appl. Environ. Microbiol. 69: 2126—2132. PMID 12676692.
- ^ Waditee, R., Tanaka, Y., Aoki, K., Hibino, T., Jikuya, H., Takano, J., Takabe, T. and Takabe, T. (2003). „Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica”. J. Biol. Chem. 278: 4932—4942. PMID 12466265.
Literatura
[uredi | uredi izvor]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[uredi | uredi izvor]- Choline+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
