Beta-kubebenska sintaza
Изглед
Beta-kubebenska sintaza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.2.3.128 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Beta-kubebenska sintaza (EC 4.2.3.128, cop4, Mg25) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (ciklizacija, formira beta-kubeben).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (2E,6E)-farnezil difosfat beta-kubeben + difosfat
Ovaj enzim je izolovan iz gljive Coprinus cinereus.
Reference
[уреди | уреди извор]- ^ Lee, S. & Chappell, J. (2008). „Biochemical and genomic characterization of terpene synthases in Magnolia grandiflora”. Plant Physiol. 147: 1017—1033. PMID 18467455.
- ^ Agger, S., Lopez-Gallego, F. and Schmidt-Dannert, C. (2009). „Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus”. Mol. Microbiol. 72: 1181—1195. PMID 19400802.
- ^ Lopez-Gallego, F., Agger, S.A., Abate-Pella, D., Distefano, M.D. and Schmidt-Dannert, C. (2010). „Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers”. Chembiochem. 11: 1093—1106. PMID 20419721.
- ^ Lopez-Gallego, F., Wawrzyn, G.T. and Schmidt-Dannert, C. (2010). „Selectivity of fungal sesquiterpene synthases: role of the active site’s H-1α loop in catalysis”. Appl. Environ. Microbiol. 76: 7723—7733. PMID 20889795.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Beta-cubebene+synthase на US National Library of Medicine Medical Subject Headings (MeSH)