Propionil-KoA C2-trimetiltridekanoiltransferaza
| Propionil-KoA C2-trimetiltridekanoiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.154 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Propionil-KoA C2-trimetiltridekanoiltransferaza (EC 2.3.1.154, 3-oksopristanoil-KoA hidrolaza, 3-oksopristanoil-KoA tiolaza, peroksizom sterolni nosilac protein tiolaza, sterolni nosilac protein, oksopristanoil-KoA tiolaza, peroksizomalna 3-oksoacil koenzim A tiolaza, SCPx, 4,8,12-trimetiltridekanoil-KoA:propanoil-KoA 2-C-4,8,12-trimetiltridekanoiltransferaza) je enzim sa sistematskim imenom 4,8,12-trimetiltridekanoil-KoA:propanoil-KoA C2-4,8,12-trimetiltridekanoiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4,8,12-trimetiltridekanoil-KoA + propanoil-KoA KoA + 3-oksopristanoil-KoA
Peroksizomal protein sterolni nosilac protein X (SCPx) kombinuje ovu tiolaznu aktivnost sa funkcijom nosiloca. On učestvuje u beta oksidaciji razgranatih masnih kiselina u peroksizomima.
Reference
[уреди | уреди извор]- ^ Seedorf, U., Brysch, P., Engel, T., Schrage, K. and Assmann, G. (1994). „Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity”. J. Biol. Chem. 269: 21277—21283. PMID 8063752.
- ^ Wanders, R.J.A., Denis, S., Wouters, F., Wirtz, K.W.A. and Seedorf, U. (1997). „Sterol carrier protein X (SCPx) is a peroxisomal branched-chain β-ketothiolase specifically reacting with 3-oxo-pristanoyl-CoA: a new, unique role for SCPx in branched-chain fatty acid metabolism in peroxisomes”. Biochem. Biophys. Res. Commun. 236: 565—569. PMID 9245689.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Propionyl-CoA+C2-trimethyltridecanoyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
