Diacilglicerol O-aciltransferaza
(преусмерено са EC 2.3.1.20)
| Diacilglicerol O-aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.20 | ||||||||
| CAS broj | 9029-98-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Diacilglicerol O-aciltransferaza (EC 2.3.1.20, digliceridna aciltransferaza, 1,2-diacilglicerolna aciltransferaza, diacilglicerolna aciltransferaza, digliceridna O-aciltransferaza, palmitoil-KoA-sn-1,2-diacilglicerol aciltransferaza, acil-KoA:1,2-diacilglicerol O-aciltransferaza) je enzim sa sistematskim imenom acil-KoA:1,2-diacil-sn-glicerol O-aciltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acil-KoA + 1,2-diacil-sn-glicerol KoA + triacilglicerol
Palmitoil-KoA i drugi dugolančani acil-KoAs mogu da deluju kao donori.
Reference
[уреди | уреди извор]- ^ Coleman, R. & Bell, R.M. (1976). „Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols”. J. Biol. Chem. 251: 4537—4543. PMID 947894.
- ^ Grigor, M.R. & Bell, R.M. (1982). „Separate monoacylglycerol and diacylglycerol acyltransferases function in intestinal triacylglycerol synthesis”. Biochim. Biophys. Acta. 712: 464—472. PMID 6289909.
- ^ Kawasaki, T. & Snyder, F. (1988). „Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells”. J. Biol. Chem. 263: 2593—2596. PMID 3422635.
- ^ Weiss, S.B., Kennedy, E.P. and Kiyasu, J.Y. (1960). „The enzymatic synthesis of triglycerides”. J. Biol. Chem. 235: 40—44. PMID 13843753.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Diacylglycerol+O-acyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
