Glutamat-cisteinska ligaza
| Glutamat-cisteinska ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.2 | ||||||||
| CAS broj | 9023-64-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Glutamat-cisteinska ligaza (EC 6.3.2.2, gama-glutamilcisteinska sintetaza, gama-glutamil-L-cistein sintetaza, gama-glutamilcisteinilna sintetaza) je enzim sa sistematskim imenom L-glutamat:L-cistein gama-ligaza (formira ADP).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim može da koristi L-aminoheksanoat umesto glutamata.
Reference
[уреди | уреди извор]- ^ MacKinnon, C.M., Carter, P.E., Smyth, S.J., Dunbar, B. and Fothergill, J.E. (1987). „Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence”. Eur. J. Biochem. 169: 547—553. PMID 3500856.
- ^ Snoke, J.E., Yanari, S. and Bloch, K. (1953). „Synthesis of glutathione from γ-glutamylcysteine”. J. Biol. Chem. 201: 573—586. PMID 13061393.
- ^ Mandeles, S. & Bloch, K. (1955). „Enzymatic synthesis of γ-glutamylcysteine”. J. Biol. Chem. 214: 639—646. PMID 14381401.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Glutamate---cysteine+ligase на US National Library of Medicine Medical Subject Headings (MeSH)
