Н-миристилтрансфераза 1
| N-miristoiltransferaza 1 | |||||||||||
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| Dostupne strukture | |||||||||||
| 1RXT, 3IU1, 3IU2, 3IWE, 3JTK | |||||||||||
| Identifikatori | |||||||||||
| Simboli | NMT1; NMT | ||||||||||
| Vanjski ID | OMIM: 160993 MGI: 102579 HomoloGene: 69027 GeneCards: NMT1 Gene | ||||||||||
| EC broj | 2.3.1.97 | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 4836 | 18107 | |||||||||
| Ensembl | ENSG00000136448 | ENSMUSG00000020936 | |||||||||
| UniProt | P30419 | O70310 | |||||||||
| RefSeq (mRNA) | NM_021079.3 | NM_008707.3 | |||||||||
| RefSeq (protein) | NP_066565.1 | NP_032733.1 | |||||||||
| Lokacija (UCSC) |
Chr 17: 43.14 - 43.19 Mb |
Chr 11: 103.03 - 103.07 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Glicilpeptid N-tetradekanoiltransferaza 1 (miristil-CoA:protein N-miristiltransferaza 1, NMT-1) je enzim koji je kod ljudi kodiran NMT1 genom.[1][2]
Reference
[уреди | уреди извор]- ^ Duronio RJ, Reed SI, Gordon JI (1992). „Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae”. Proc Natl Acad Sci U S A. 89 (9): 4129—33. PMC 525646
. PMID 1570339. doi:10.1073/pnas.89.9.4129.
- ^ „Entrez Gene: NMT1 N-myristoyltransferase 1”.
Literatura
[уреди | уреди извор]- Rajala RV; Datla RS; Moyana TN; et al. (2000). „N-myristoyltransferase.”. Mol. Cell. Biochem. 204 (1–2): 135—55. PMID 10718634. doi:10.1023/A:1007012622030.
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- Wice BM, Gordon JI (1992). „A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexin”. J. Cell Biol. 116 (2): 405—22. PMC 2289284 . PMID 1530946. doi:10.1083/jcb.116.2.405.
- Mumby SM, Heukeroth RO, Gordon JI, Gilman AG (1990). „G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells”. Proc. Natl. Acad. Sci. U.S.A. 87 (2): 728—32. PMC 53339 . PMID 2153964. doi:10.1073/pnas.87.2.728.
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- Tashiro A, Shoji S, Kubota Y (1990). „Antimyristoylation of the gag proteins in the human immunodeficiency virus-infected cells with N-myristoyl glycinal diethylacetal resulted in inhibition of virus production”. Biochem. Biophys. Res. Commun. 165 (3): 1145—54. PMID 2692561. doi:10.1016/0006-291X(89)92722-8.
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- Sigal CT; Zhou W; Buser CA; et al. (1995). „Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids”. Proc. Natl. Acad. Sci. U.S.A. 91 (25): 12253—7. PMC 45415 . PMID 7527558. doi:10.1073/pnas.91.25.12253.
- Zhou W, Parent LJ, Wills JW, Resh MD (1994). „Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids”. J. Virol. 68 (4): 2556—69. PMC 236733 . PMID 8139035.
- Kobayashi M, Takamatsu K, Saitoh S, Noguchi T (1993). „Myristoylation of hippocalcin is linked to its calcium-dependent membrane association properties”. J. Biol. Chem. 268 (25): 18898—904. PMID 8360179.
- Morikawa Y; Hinata S; Tomoda H; et al. (1996). „Complete inhibition of human immunodeficiency virus Gag myristoylation is necessary for inhibition of particle budding”. J. Biol. Chem. 271 (5): 2868—73. PMID 8576268. doi:10.1074/jbc.271.5.2868.
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- Zhou W, Resh MD (1997). „Differential membrane binding of the human immunodeficiency virus type 1 matrix protein”. J. Virol. 70 (12): 8540—8. PMC 190946 . PMID 8970978.
- Yu W; Andersson B; Worley KC; et al. (1997). „Large-scale concatenation cDNA sequencing”. Genome Res. 7 (4): 353—8. PMC 139146 . PMID 9110174. doi:10.1101/gr.7.4.353.
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
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- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
