Alfa-farnezenska sintaza

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Alfa-farnezenska sintaza
Alfa-farnezenska sintaza
Identifikatori
EC broj	4.2.3.46
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Alfa-farnezenska sintaza (EC 4.2.3.46, (E,E)-alfa-farnezen sintaza, AFS1, MdAFS1) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat lijaza (formira (3E,6E)-alfa-farnezen).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

(2E,6E)-farnezil difosfat

\rightleftharpoons

(3E,6E)-alfa-farnezen + difosfat

Reference

^ Pechous, S.W. & Whitaker, B.D. (2004). „Cloning and functional expression of an (E,E)-α-farnesene synthase cDNA from peel tissue of apple fruit”. Planta. 219: 84—94. PMID 14740213.
^ Green, S., Squire, C.J., Nieuwenhuizen, N.J., Baker, E.N. and Laing, W. (2009). „Defining the potassium binding region in an apple terpene synthase”. J. Biol. Chem. 284: 8661—8669. PMID 19181671.
^ Nieuwenhuizen, N.J., Wang, M.Y., Matich, A.J., Green, S.A., Chen, X., Yauk, Y.K., Beuning, L.L., Nagegowda, D.A., Dudareva, N. and Atkinson, R.G. (2009). „Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa)”. J. Exp. Bot. 60: 3203—3219. PMID 19516075.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Alpha-farnesene+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Pechous, S.W. & Whitaker, B.D. (2004). „Cloning and functional expression of an (E,E)-α-farnesene synthase cDNA from peel tissue of apple fruit”. Planta. 219: 84—94. PMID 14740213.

[2] Green, S., Squire, C.J., Nieuwenhuizen, N.J., Baker, E.N. and Laing, W. (2009). „Defining the potassium binding region in an apple terpene synthase”. J. Biol. Chem. 284: 8661—8669. PMID 19181671.

[3] Nieuwenhuizen, N.J., Wang, M.Y., Matich, A.J., Green, S.A., Chen, X., Yauk, Y.K., Beuning, L.L., Nagegowda, D.A., Dudareva, N. and Atkinson, R.G. (2009). „Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa)”. J. Exp. Bot. 60: 3203—3219. PMID 19516075.

[1]

[2]

[3]

p r u Ugljenično-kiseonične lijaze (EC 4.2) (prvenstveno dehidrataze)
4.2.1: Hidro-lijaze	Karbonatna dehidrataza Fumaraza Akonitaza Enolaza Alfa Enolaza 2 Enoil-KoA hidrataza/3-Hidroksiacil ACP dehidraza Metilglutakonil-KoA hidrataza Triptofanska sintaza Cistationin beta sintaza Porfobilinogen sintaza 3-Izopropilmalat dehidrataza Urokanaza Uroporfirinogen III sintaza Nitrilna hidrataza
4.2.2: Delovanje na polisaharide	Hijaluronatna lijaza
4.2.3: Delovanje na fosfate	Treoninska sintaza
4.2.99: Druge	Karboksimetiloksisukcinatna lijaza Hidroperoksidna lijaza

p r u Enzimi
Teme	Aktivno mesto Alosterna regulacija Mesto vezivanja Katalitički perfektan enzim Koenzim Kofaktor Kooperativnost EC broj Enzimska kataliza Inhibicija enzima Enzimska kinetika Lajnviver—Berkov dijagram Mihaelis—Mentenina kinetika Spisak enzima
Tipovi	EC1 Oksidoreduktaze /spisak EC2 Transferaze /spisak EC3 Hidrolaze /spisak EC4 Lijaze /spisak EC5 Izomeraze /spisak EC6 Ligaze /spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6