CHST8

CHST8
Identifikatori
Alijasi	CHST8
Spoljašnji ID	OMIM: 610190 MGI: 1916197 HomoloGene: 41483 GeneCards: CHST8
Genska lokacija (miš) Hr. Chromosome 7 (mouse) Band 7|7 B2 Start 34,373,893 bp Kraj 34,512,136 bp
Genska ontologija Molecular function • transferase activity • sulfotransferase activity • N-acetylgalactosamine 4-O-sulfotransferase activity Cellular component • sastavni deo membrane • Golgi membrane • Goldžijev aparat • membrana Biological process • sulfur compound metabolic process • razvoj centralnog nervnog sistema • carbohydrate biosynthetic process • hormone biosynthetic process • proteoglycan biosynthetic process • Metabolizam ugljenih hidrata Sources:Amigo / QuickGO
Ortolozi
Vrste	Čovek	Miš
Entrez	64377	68947
Ensembl	ENSG00000124302	ENSMUSG00000060402
UniProt	Q9H2A9	Q8BQ86
RefSeq (mRNA)	NM_001127895 NM_001127896 NM_022467	NM_175140
RefSeq (protein)	NP_001121367 NP_001121368 NP_071912	NP_780349
Location (UCSC)	n/a	Chr 7: 34.37 – 34.51 Mb
PubMed search
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Ugljeno hidratna sulfotransferaza 8 (eng. Carbohydrate sulfotransferase 8) je enzim koji je kod ljudi kodiran istoimenim genom CHST8, nalazi se na dugom kraku hromozoma 19. Dužina polipeptidnog lanca je 424 aminokiselina, a molekulska težina 48 834.

Literatura

• Xia G., Evers M.R., Kang H.-G., Schachner M., Baenziger J.U. (2000). „Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase.”. J. Biol. Chem. 275: 38402 — 38409. PMID 10988300. doi:10.1074/jbc.M007821200. CS1 održavanje: Višestruka imena: spisak autora (veza)
• Hiraoka N., Misra A., Belot F., Hindsgaul O., Fukuda M. (2001). „Molecular cloning and expression of two distinct human N-acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1->4GlcNAc beta 1->R in both N- and O-glycans.”. Glycobiology. 11: 495 — 504. PMID 11445554. doi:10.1093/glycob/11.6.495. CS1 održavanje: Višestruka imena: spisak autora (veza)
• „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14: 2121 — 2127. 2004. PMID 15489334. doi:10.1101/gr.2596504. 
• Barret A., Forestier L., Deslys J.-P., Julien R., Gallet P.F. (2005). „Glycosylation-related gene expression in prion diseases: PrPSc accumulation in scrapie infected GT1 cells depends on beta-1,4-linked GalNAc-4-SO4 hyposulfation.”. J. Biol. Chem. 280: 10516 — 10523. PMID 15632154. doi:10.1074/jbc.M412635200. CS1 održavanje: Višestruka imena: spisak autora (veza)