Kohezin
Appearance
Hromatidni kohezioni protein 1 | |
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![]() Kohezinski kompleks se sastoji od SCC1 i SMC1 proteina.[1] | |
Identifikatori | |
Simbol | MCD1 |
Alt. simboli | PDS3, RHC21, SCC1 |
Entrez | 851561 |
PDB | 1W1W |
UniProt | Q12158 |
Kohezinska podjedinica SCC3 | |
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Identifikatori | |
Simbol | IRR1 |
Alt. simboli | SCC3 |
Entrez | 854786 |
UniProt | P40541 |
Strukturno održavanje hromozomskog proteina 1 | |
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Identifikatori | |
Simbol | SMC1 |
Alt. simboli | CHL10 |
Entrez | 850540 |
PDB | 1W1W |
UniProt | P32908 |
Strukturno održavanje hromozomskog proteina 3 | |
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Identifikatori | |
Simbol | SMC3 |
Alt. simboli | J1049 |
Entrez | 853371 |
UniProt | P47037 |
Kohesin je proteinski kompleks koji reguliše separaciju hromatida tokom ćelijske deobe, bilo mitoze ili mejoze.[2][3][4]
Reference[uredi | uredi izvor]
- ^ PDB: 1W1W; Haering CH, Schoffnegger D, Nishino T, Helmhart W, Nasmyth K, Löwe J (2004). „Structure and stability of cohesin's Smc1-kleisin interaction”. Mol. Cell. 15 (6): 951—64. PMID 15383284. doi:10.1016/j.molcel.2004.08.030.
- ^ Michaelis C, Ciosk R, Nasmyth K (1997). „Cohesins: chromosomal proteins that prevent premature separation of sister chromatids”. Cell. 91 (1): 35—45. PMID 9335333. doi:10.1016/S0092-8674(01)80007-6.
- ^ Guacci V, Koshland D, Strunnikov A (1997). „A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae”. Cell. 91 (1): 47—57. PMC 2670185
. PMID 9335334. doi:10.1016/S0092-8674(01)80008-8.
- ^ Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K (1999). „Yeast Cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication”. Genes Dev. 13 (3): 320—33. PMC 316435
. PMID 9990856. doi:10.1101/gad.13.3.320.
Literatura[uredi | uredi izvor]
- Michaelis C, Ciosk R, Nasmyth K (1997). „Cohesins: chromosomal proteins that prevent premature separation of sister chromatids”. Cell. 91 (1): 35—45. PMID 9335333. doi:10.1016/S0092-8674(01)80007-6.
- Guacci V, Koshland D, Strunnikov A (1997). „A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae”. Cell. 91 (1): 47—57. PMC 2670185
. PMID 9335334. doi:10.1016/S0092-8674(01)80008-8.
- Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K (1999). „Yeast Cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication”. Genes Dev. 13 (3): 320—33. PMC 316435
. PMID 9990856. doi:10.1101/gad.13.3.320.
- Uhlmann F, Lottspeich F, Nasmyth K (1999). „Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1”. Nature. 400 (6739): 37—42. PMID 10403247. doi:10.1038/21831.