Iduronatna 2-sulfataza

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PMC	članci
PubMed	članci
NCBI	proteini

Iduronatna 2-sulfataza
Iduronatna 2-sulfataza
Identifikatori
EC broj	3.1.6.13
CAS broj	50936-59-9
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Iduronatna 2-sulfataza (EC 3.1.6.13, hondroitinsulfataza, idurono-2-sulfataza, iduronid-2-sulfat sulfataza, L-iduronosulfataza, L-idurono sulfatna sulfataza, iduronatna sulfataza, sulfo-L-iduronatna sulfataza, L-iduronat 2-sulfatna sulfataza, sulfoiduronatna sulfohidrolaza, 2-sulfo-L-iduronat 2-sulfataza, iduronat-2-sulfat sulfataza, iduronat sulfatna sulfataza) je enzim sa sistematskim imenom L-iduronat-2-sulfat 2-sulfohidrolaza.^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

hidroliza 2-sulfatnih grupa L-iduronat 2-sulfatnih jedinica dermatan sulfata, heparan sulfata i heparina

Reference

^ Archer, I.M., Harper, P.S. and Wusteman, F.S. (1982). „Multiple forms of iduronate 2-sulphate sulphatase in human tissues and body fluids”. Biochim. Biophys. Acta. 708: 134—140. PMID 6816283.
^ Bach, J., Eisenberg, F., Cantz, M. and Neufeld, E.C. (1973). „The defect in the Hunter syndrome: deficiency of sulfoiduronate sulfatase”. Proc. Natl. Acad. Sci. USA. 70: 2134—2138. PMID 4269173.
^ DiNatale, P. & Ronsivalle, L. (1981). „Identification and partial characterization of two enzyme forms of iduronate sulfatase from human placenta”. Biochim. Biophys. Acta. 661: 106—111. PMID 6945876.
^ Yutaka, T., Fluharty, A.L., Stevens, R.L. and Kihara, H. (1982). „Purification and some properties of human liver iduronate sulfatase”. J. Biochem. (Tokyo). 91: 433—441. PMID 6950934.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Iduronate-2-sulfatase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Archer, I.M., Harper, P.S. and Wusteman, F.S. (1982). „Multiple forms of iduronate 2-sulphate sulphatase in human tissues and body fluids”. Biochim. Biophys. Acta. 708: 134—140. PMID 6816283.

[2] Bach, J., Eisenberg, F., Cantz, M. and Neufeld, E.C. (1973). „The defect in the Hunter syndrome: deficiency of sulfoiduronate sulfatase”. Proc. Natl. Acad. Sci. USA. 70: 2134—2138. PMID 4269173.

[3] DiNatale, P. & Ronsivalle, L. (1981). „Identification and partial characterization of two enzyme forms of iduronate sulfatase from human placenta”. Biochim. Biophys. Acta. 661: 106—111. PMID 6945876.

[4] Yutaka, T., Fluharty, A.L., Stevens, R.L. and Kihara, H. (1982). „Purification and some properties of human liver iduronate sulfatase”. J. Biochem. (Tokyo). 91: 433—441. PMID 6950934.

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п р у Enzimi
Teme	Aktivno mesto Alosterna regulacija Mesto vezivanja Katalitički perfektan enzim Koenzim Kofaktor Kooperativnost EC broj Enzimska kataliza Inhibicija enzima Enzimska kinetika Lajnviver—Berkov dijagram Mihaelis—Mentenina kinetika Spisak enzima
Tipovi	EC1 Oksidoreduktaze /spisak EC2 Transferaze /spisak EC3 Hidrolaze /spisak EC4 Lijaze /spisak EC5 Izomeraze /spisak EC6 Ligaze /spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6