(+)-Alfa-pinenska sintaza
Изглед
(+)-Alfa-pinenska sintaza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.2.3.121 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(+)-Alfa-pinenska sintaza (EC 4.2.3.121, (+)-alfa-pinenska ciklaza, ciklaza I) je enzim sa sistematskim imenom geranil-difosfat difosfat-lijaza (ciklizacija, formira (+)-alfa-pinen).[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- geranil difosfat (+)-alfa-pinen + difosfat
Ciklaza I iz Salvia officinalis formira jednake količine (-)-alfa-pinena i (-)-kamfena.
Reference
[уреди | уреди извор]- ^ Gambliel, H. & Croteau, R. (1984). „Pinene cyclases I and II. Two enzymes from sage (Salvia officinalis) which catalyze stereospecific cyclizations of geranyl pyrophosphate to monoterpene olefins of opposite configuration”. J. Biol. Chem. 259: 740—748. PMID 6693393.
- ^ Croteau, R.; Satterwhite, D.M.; Cane, D.E.; Chang, C.C. (1988). „Biosynthesis of monoterpenes. Enantioselectivity in the enzymatic cyclization of (+)- and (-)-linalyl pyrophosphate to (+)- and (-)-pinene and (+)- and (-)-camphene”. J. Biol. Chem. 263: 10063—10071. PMID 3392006.
- ^ Wagschal, K.C.; Pyun, H.J.; Coates, R.M.; Croteau, R. (1994). „Monoterpene biosynthesis: isotope effects associated with bicyclic olefin formation catalyzed by pinene synthases from sage (Salvia officinalis)”. Arch. Biochem. Biophys. 308: 477—487. PMID 8109978.
- ^ Pyun, H.J.; Wagschal, K.C.; Jung, D.I.; Coates, R.M.; Croteau, R. (1994). „Stereochemistry of the proton elimination in the formation of (+)- and (-)-α-pinene by monoterpene cyclases from sage (Salvia officinalis)”. Arch. Biochem. Biophys. 308: 488—496. PMID 8109979.
- ^ Phillips, M.A.; Savage, T.J.; Croteau, R. (1999). „Monoterpene synthases of loblolly pine (Pinus taeda) produce pinene isomers and enantiomers”. Arch. Biochem. Biophys. 372: 197—204. PMID 10562434.
- ^ Phillips, M.A.; Wildung, M.R.; Williams, D.C.; Hyatt, D.C.; Croteau, R. (2003). „cDNA isolation, functional expression, and characterization of (+)-α-pinene synthase and (-)-α-pinene synthase from loblolly pine (Pinus taeda): stereocontrol in pinene biosynthesis”. Arch. Biochem. Biophys. 411: 267—276. PMID 12623076.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- (+)-alpha-pinene+synthase на US National Library of Medicine Medical Subject Headings (MeSH)