1-Acilglicerol-3-fosfat O-aciltransferaza
| 1-acilglicerol-3-fosfat O-aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.51 | ||||||||
| CAS broj | 51901-16-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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1-acilglicerol-3-fosfat O-aciltransferaza (EC 2.3.1.51, 1-acil-sn-glicero-3-fosfatna aciltransferaza, 1-acil-sn-glicerol 3-fosfatna aciltransferaza, 1-acilglicero-3-fosfatna aciltransferaza, 1-acilglicerolfosfatna aciltransferaza, 1-acilglicerofosfatna aciltransferaza, lizofosfatidinsko kiselinska aciltransferaza) je enzim sa sistematskim imenom acil-KoA:1-acil-sn-glicerol-3-fosfat 2-O-aciltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acil-KoA + 1-acil-sn-glicerol 3-fosfat KoA + 1,2-diacil-sn-glicerol 3-fosfat
Acil-[acil-nosilac protein] može takođe da deluje kao acil donor. Životinjski enzim je specifičan po transferu nezasićenih masnih acil grupa.
Reference
[уреди | уреди извор]- ^ Frentzen, M., Heinz, E., McKeon, T.A. and Stumpf, P.K. (1983). „Specificities and selectivities of glycerol-3-phosphate acyltransferase and monoacylglycerol-3-phosphate acyltransferase from pea and spinach chloroplasts”. Eur. J. Biochem. 129: 629—636. PMID 6825679.
- ^ Hill, E.E. & Lands, W.E.M. (1968). „Incorporation of long-chain and polyunsaturated acids into phosphatidate and phosphatidylcholine”. Biochim. Biophys. Acta. 152: 645—648. PMID 5661029.
- ^ Yamashita, S., Hosaka, K. and Numa, S. (1973). „Acyl-donor specificities of partially purified 1-acylglycerophosphate acyltransferase, 2-acylglycerophosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes”. Eur. J. Biochem. 38: 25—31. PMID 4774123.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- 1-acylglycerol-3-phosphate+O-acyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
