CHST2

CHST2
Identifikatori
Alijasi	CHST2
Spoljašnji ID	OMIM: 603798 MGI: 1891160 HomoloGene: 3150 GeneCards: CHST2
Genska lokacija (miš) Hr. Chromosome 9 (mouse) Band 9|9 E3.3 Start 95,281,345 bp Kraj 95,288,775 bp
Obrazac RNK izražavanja More reference expression data
Genska ontologija Molecular function • transferase activity • sulfotransferase activity • N-acetylglucosamine 6-O-sulfotransferase activity Cellular component • саставни део мембране • Golgi membrane • trans-Golgi network • intrinsic component of Golgi membrane • мембрана • Голџијев апарат Biological process • multicellular organism development • sulfur compound metabolic process • запаљенска реакција • keratan sulfate biosynthetic process • N-acetylglucosamine metabolic process • Метаболизам угљених хидрата Sources:Amigo / QuickGO
Ortolozi
Vrste	Čovek	Miš
Entrez	9435	54371
Ensembl	ENSG00000175040	ENSMUSG00000033350
UniProt	Q9Y4C5	Q80WV3
RefSeq (mRNA)	NM_004267	NM_018763
RefSeq (protein)	NP_004258	NP_061233
Location (UCSC)	n/a	Chr 9: 95.28 – 95.29 Mb
PubMed search
Wikidata
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Ugljeno hidratna sulfotransferaza 2 je enzim koji je kod ljudi kodiran genom CHST2, nalazi se na kratkom (p) kraku 3. hromozoma. Dužina polipeptidnog lanca proteina je 530 aminokiselina, a molekulska težina 57.857.7

Dopunska literatura

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• Sakaguchi H, Kitagawa H, Sugahara K (2000). „Functional expression and genomic structure of human N-acetylglucosamine-6-O-sulfotransferase that transfers sulfate to beta-N-acetylglucosamine at the nonreducing end of an N-acetyllactosamine sequence.”. Biochim. Biophys. Acta. 1523 (2–3): 269—76. PMID 11042394. doi:10.1016/s0304-4165(00)00136-7. 
• Okuda T, Mita S, Yamauchi S, et al. (2001). „Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase.”. J. Biochem. 128 (5): 763—70. PMID 11056388. doi:10.1093/oxfordjournals.jbchem.a022813. 
• Li X, Tu L, Murphy PG, et al. (2001). „CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin.”. J. Leukoc. Biol. 69 (4): 565—74. PMID 11310842. S2CID 8888883. doi:10.1189/jlb.69.4.565 . 
• Uchimura K, El-Fasakhany FM, Hori M, et al. (2002). „Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.”. J. Biol. Chem. 277 (6): 3979—84. PMID 11726653. doi:10.1074/jbc.M106587200 . 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. Bibcode:2002PNAS...9916899M. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899 . 
• Grunwell JR, Rath VL, Rasmussen J, et al. (2003). „Characterization and mutagenesis of Gal/GlcNAc-6-O-sulfotransferases.”. Biochemistry. 41 (52): 15590—600. PMID 12501187. doi:10.1021/bi0269557. 
• de Graffenried CL, Bertozzi CR (2003). „Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis.”. J. Biol. Chem. 278 (41): 40282—95. PMID 12855678. doi:10.1074/jbc.M304928200 . 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet. 36 (1): 40—5. PMID 14702039. doi:10.1038/ng1285 . 
• de Graffenried CL, Bertozzi CR (2004). „The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity.”. J. Biol. Chem. 279 (38): 40035—43. PMID 15220337. doi:10.1074/jbc.M405709200 . 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504. 
• Chen L, Ichihara-Tanaka K, Muramatsu T (2005). „Role of the carboxyl-terminal region in the activity of N-acetylglucosamine 6-o-sulfotransferase-1.”. J. Biochem. 136 (5): 659—64. PMID 15632306. doi:10.1093/jb/mvh162. 
• Kanoh A, Seko A, Ideo H, et al. (2007). „Ectopic expression of N-acetylglucosamine 6-O-sulfotransferase 2 in chemotherapy-resistant ovarian adenocarcinomas.”. Glycoconj. J. 23 (5–6): 453—60. PMID 16897186. S2CID 22628478. doi:10.1007/s10719-006-6979-6.