CHST4

CHST4
Identifikatori
Alijasi	CHST4
Spoljašnji ID	MGI: 1349479 HomoloGene: 4216 GeneCards: CHST4
Genska lokacija (miš) Hr. Chromosome 8 (mouse) Band 8|8 D3 Start 110,755,785 bp Kraj 110,766,372 bp
Obrazac RNK izražavanja More reference expression data
Genska ontologija Molecular function • transferase activity • sulfotransferase activity • N-acetylglucosamine 6-O-sulfotransferase activity Cellular component • саставни део мембране • Голџијев апарат • intrinsic component of Golgi membrane • мембрана • Golgi membrane • trans-Golgi network Biological process • cell-cell signaling • Ćelijska adhezija • GO:0046730, GO:0046737, GO:0046738, GO:0046736 имуни одговор • O-glycan processing • sulfur compound metabolic process • protein sulfation • запаљенска реакција • N-acetylglucosamine metabolic process • keratan sulfate biosynthetic process • Метаболизам угљених хидрата Sources:Amigo / QuickGO
Ortolozi
Vrste	Čovek	Miš
Entrez	10164	26887
Ensembl	ENSG00000140835	ENSMUSG00000035930
UniProt	Q8NCG5	Q9R1I1
RefSeq (mRNA)	NM_005769 NM_001166395	NM_011998
RefSeq (protein)	NP_001159867 NP_005760	NP_036128
Location (UCSC)	n/a	Chr 8: 110.76 – 110.77 Mb
PubMed search
Wikidata
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Ugljeno hidratna sulfotransferaza 4 (eng. Carbohydrate sulfotransferase 4) je enzim koji je kod ljudi kodiran istoimenim genom CHST4, nalazi se na kratkom kraku 16 hromozoma. Dužina polipeptidnog lanca je 386 aminokiselina, a molekulska težina 45.134.

Literatura

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• Hemmerich S; Lee JK; Bhakta S; et al. (2001). „Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family”. Glycobiology. 11 (1): 75—87. PMID 11181564. doi:10.1093/glycob/11.1.75 . 
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• de Graffenried CL, Bertozzi CR (2004). „The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity”. J. Biol. Chem. 279 (38): 40035—43. PMID 15220337. doi:10.1074/jbc.M405709200 . 
• Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504. 
• Otsuki T; Ota T; Nishikawa T; et al. (2007). „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries”. DNA Res. 12 (2): 117—26. PMID 16303743. doi:10.1093/dnares/12.2.117 . 
• Timson G; Banavali S; Gutierrez MI; et al. (2006). „High level expression of N-acetylgluosamine-6-O-sulfotransferase is characteristic of a subgroup of paediatric precursor-B acute lymphoblastic leukaemia”. Cancer Lett. 242 (2): 239—44. PMID 16386360. doi:10.1016/j.canlet.2005.11.012.