Ekso-(1-4)-α-D-glukanska lijaza
| Ekso-(1-4)-α-D-glukanska lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.2.13 | ||||||||
| CAS broj | 148710-18-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ekso-(1-4)-α-D-glukanska lijaza (EC 4.2.2.13, alfa-(1->4)-glukan 1,5-anhidro-D-fruktozna eliminaza, alfa-1,4-glukan ekso-lijaza, alfa-1,4-glukan lijaza, Glaza) je enzim sa sistematskim imenom (1->4)-alfa-D-glukan ekso-4-lijaza (formira 1,5-anhidro-D-fruktoza).[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- linearni alfa-glukan (N-1) 1,5-anhidro-D-fruktoza + D-glukoza
Ovaj enzim katalizuje sekvencinu degradaciju (1->4)-alfa-D-glukana sa neredukujućeg kraja.
Reference
[уреди | уреди извор]- ^ Yu, S., Kenne, L., Pedersén, M. (1993). „α-1,4-Glucan lyase, a new class of starch/glycogen degrading enzyme. I. Efficient purification and characterization from red seaweeds”. Biochim. Biophys. Acta. 1156: 313—320. PMID 8461323.
- ^ Yu, S., Pedersén, M. (1993). „α-1,4-Glucan lyase, a new class of starch/glycogen degrading enzyme. II. Subcellular localization and partial amino-acid sequence”. Planta. 191: 137—142. PMID 7763826.
- ^ Yu, S., Ahmad, T., Kenne, L. and Pedersén, M. (1995). „α-1,4-Glucan lyase, a new class of starch/glycogen degrading enzyme. III. Substrate specificity, mode of action, and cleavage mechanism”. Biochim. Biophys. Acta. 1244: 1—9. PMID 7766642.
- ^ Yu, S., Christensen, T.M., Kragh, K.M., Bojsen, K. and Marcussen, J. (1997). „Efficient purification, characterization and partial amino acid sequencing of two α-1,4-glucan lyases from fungi”. Biochim. Biophys. Acta. 1339: 311—320. PMID 9187252.
- ^ Yu, S., Bojsen, K., Svensson, B. and Marcussen, J. (1999). „α-1,4-glucan lyases producing 1,5-anhydro-D-fructose from starch and glycogen have sequence similarity to α-glucosidases”. Biochim. Biophys. Acta. 1433: 1—15. PMID 10446355.
- ^ Lee, S.S., Yu, S. and Withers, S.G. (2002). „α-1,4-Glucan lyase performs a trans-elimination via a nucleophilic displacement followed by a syn-elimination”. J. Am. Chem. Soc. 124: 4948—4949. PMID 11982345.
- ^ Lee, S.S., Yu, S. and Withers, S.G. (2003). „Detailed dissection of a new mechanism for glycoside cleavage: α-1,4-glucan lyase”. Biochemistry. 42: 13081—13090. PMID 14596624.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- >4)-alpha-D-glucan%20lyase Exo-(1->4)-alpha-D-glucan+lyase на US National Library of Medicine Medical Subject Headings (MeSH)
