Fenilalanin dehidrogenaza
| Fenilalanin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.1.20 | ||||||||
| CAS broj | 69403-12-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fenilalanin dehidrogenaza (EC 1.4.1.20, L-fenilalaninska dehidrogenaza, PHD) je enzim sa sistematskim imenom L-fenilalanin:NAD+ oksidoreduktaza (deaminacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-fenilalanin +H2O + NAD+ fenilpiruvat + NH3 + NADH + H+
Enzimi iz Bacillus badius i Sporosarcina ureae su visoko specifični za L-fenilalanin; dok enzim iz Bacillus sphaericus takođe deluje na L-tirozin.
Reference
[уреди | уреди извор]- ^ Asano, Y., Nakazawa, A. and Endo, K. (1987). „Novel phenylalanine dehydrogenases from Sporosarcina ureae and Bacillus sphaericus. Purification and characterization”. J. Biol. Chem. 262: 10346—10354. PMID 3112142.
- ^ Asano, Y., Nakazawa, A., Endo, K., Hibino, Y., Ohmori, M., Numao, N. and Kondo, K. (1987). „Phenylalanine dehydrogenase of Bacillus badius. Purification, characterization and gene cloning”. Eur. J. Biochem. 168: 153—159. PMID 3311741.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Phenylalanine+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
