Kanamicin kinaza
| Kanamicin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.95 | ||||||||
| CAS broj | 62213-36-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Kanamicin kinaza (EC 2.7.1.95, neomicin-kanamicinska fosfotransferaza) je enzim sa sistematskim imenom ATP:kanamicin 3'-O-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim takođe deluje na antibiotike neomicin, paromomicin, neamin, paromamin, vistamicin i gentamicin A. Enzim iz Pseudomonas aeruginosa takođe deluje na butirozin.
Reference
[уреди | уреди извор]- ^ Doi, O., Ogura, M., Tanaka, N. and Umezawa, H. (1968). „Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginosa”. Appl. Microbiol. 16: 1276—1281. PMID 4970990.
- ^ Dolin, M.I. (1957). „The Streptococcus faecalis oxidases for reduced diphosphopyridine nucleotide. III. Isolation and properties of a flavin peroxidase for reduced diphosphopyridine nucleotide”. J. Biol. Chem. 225: 557—573. PMID 13416259.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Kanamycin+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
