L-galaktoza 1-dehidrogenaza
| L-galaktoza 1-dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.316 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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L-galaktoza 1-dehidrogenaza (EC 1.1.1.316, L-GalDH, L-galaktozna dehidrogenaza) je enzim sa sistematskim imenom L-galaktoza:NAD+ 1-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-galaktoza + NAD+ L-galakto-1,4-lakton + NADH + H+
Ovaj enzim katalizuje korak u askorbatnoj biosintezi kod viših biljki (Smirnof-Vilerov put). Njegova aktivnost sa NADP+ je manje od 10% njegove aktivnosti sa NAD+.
Reference[уреди | уреди извор]
- ^ Mieda, T., Yabuta, Y., Rapolu, M., Motoki, T., Takeda, T., Yoshimura, K., Ishikawa, T. and Shigeoka, S. (2004). „Feedback inhibition of spinach L-galactose dehydrogenase by L-ascorbate”. Plant Cell Physiol. 45: 1271—1279. PMID 15509850.
- ^ Gatzek, S., Wheeler, G.L. and Smirnoff, N. (2002). „Antisense suppression of L-galactose dehydrogenase in Arabidopsis thaliana provides evidence for its role in ascorbate synthesis and reveals light modulated L-galactose synthesis”. Plant J. 30: 541—553. PMID 12047629.
- ^ Wheeler, G.L., Jones, M.A. and Smirnoff, N. (1998). „The biosynthetic pathway of vitamin C in higher plants”. Nature. 393: 365—369. PMID 9620799.
- ^ Oh, M.M., Carey, E.E. and Rajashekar, C.B. (2009). „Environmental stresses induce health-promoting phytochemicals in lettuce”. Plant Physiol. Biochem. 47: 578—583. PMID 19297184.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- L-galactose+1-dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
