NAD(P)+—protein-arginin ADP-riboziltransferaza
| NAD(P)+—protein-arginin ADP-riboziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.2.31 | ||||||||
| CAS broj | 81457-93-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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NAD(P)+—protein-arginin ADP-riboziltransferaza (EC 2.4.2.31, ADP-riboziltransferaza, mono(ADP-ribozil)transferaza, NAD+:L-arginin ADP-D-riboziltransferaza, NAD(P)+-arginin ADP-riboziltransferaza, NAD(P)+:L-arginin ADP-D-riboziltransferaza, mono-ADP-riboziltransferaza, ART, ART1, ART2, ART3, ART4, ART5, ART6, ART7, NAD(P)+---protein-arginin ADP-riboziltransferaza, NAD(P)+:protein-L-arginin ADP-D-riboziltransferaza) je enzim sa sistematskim imenom NAD+:protein-L-arginin ADP-D-riboziltransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- NAD+ + protein L-arginin nikotinamid + Nomega-(ADP-D-ribozil)-protein-L-arginin
Protein mono-ADP-ribozilation se reverzibilno posttranslaciono modifikuje, čime se utiče na regulaciju ćelijskih aktivnosti.
Reference
[уреди | уреди извор]- ^ Moss, J., Stanley, S.J. and Oppenheimer, N.J. (1979). „Substrate specificity and partial purification of a stereospecific NAD- and guanidine-dependent ADP-ribosyltransferase from avian erythrocytes”. J. Biol. Chem. 254: 8891—8894. PMID 225315.
- ^ Moss, J., Stanley, S.J. and Watkins, P.A. (1980). „Isolation and properties of an NAD- and guanidine-dependent ADP-ribosyltransferase from turkey erythrocytes”. J. Biol. Chem. 255: 5838—5840. PMID 6247348.
- ^ Ueda, K. & Hayaishi, O. (1985). „ADP-ribosylation”. Annu. Rev. Biochem. 54: 73—100. PMID 3927821.
- ^ Corda, D. & Di Girolamo, M. (2003). „Functional aspects of protein mono-ADP-ribosylation”. EMBO J. 22: 1953—1958. PMID 12727863.
- ^ Paone, G., Stevens, L.A., Levine, R.L., Bourgeois, C., Steagall, W.K., Gochuico, B.R. and Moss, J. (2006). „ADP-ribosyltransferase-specific modification of human neutrophil peptide-1”. J. Biol. Chem. 281: 17054—17060. PMID 16627471.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- NAD+---protein-arginine+ADP-ribosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
