Prenilcistein oksidaza
| Prenilcistein oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.3.5 | ||||||||
| CAS broj | 196717-99-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Prenilcistein oksidaza (EC 1.8.3.5, prenilcisteinska lijaza) je enzim sa sistematskim imenom S-prenil-L-cistein:kiseonik oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-prenil-L-cistein + O2 +H2O prenal + L-cistein +H2O2
Ovaj enzim je flavoprotein (FAD). On raskida tioetarsku vezu S-prenil-L-cisteina, kao što je S-farnezilcistein i S-geranilgeranilcistein.
Reference
[уреди | уреди извор]- ^ Zhang, L., Tschantz, W.R. and Casey, P.J. (1997). „Isolation and characterization of a prenylcysteine lyase from bovine brain”. J. Biol. Chem. 272: 23354—23359. PMID 9287348.
- ^ Tschantz, W.R., Digits, J.A., Pyun, H.J., Coates, R.M. and Casey, P.J. (2001). „Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase”. J. Biol. Chem. 276: 2321—2324. PMID 11078725.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Prenylcysteine+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)
