Sterol O-aciltransferaza
| Sterol O-aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.26 | ||||||||
| CAS broj | 9027-63-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Sterol O-aciltransferaza (EC 2.3.1.26, holestarolna aciltransferaza, sterol-estarska sintaza, sterol-estarska sintetaza, sterol-estarska sintaza, acil koenzim A-holestarol-O-aciltransferaza, acil-KoA:holestarol aciltransferaza, ACAT, acilkoenzim A:holestarol O-aciltransferaza, holestarol estarska sintaza, holestarol estarska sintetaza, holestaril estarska sintetaza) je enzim sa sistematskim imenom acil-KoA:holestarol O-aciltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acil-KoA + holesterol KoA + holesterol estar
Životinjski enzim je visoko specifičan za transfer acil grupa.
Reference
[уреди | уреди извор]- ^ Sgoutas, D.S. (1970). „Effect of geometry and position of ethylenic bond upon acyl coenzymeA--cholesterol-O-acyltransferase”. Biochemistry. 9: 1826—1833. PMID 5439042.
- ^ Spector, A.A., Mathur, S.N. and Kaduce, T.L. (1979). „Role of acylcoenzyme A: cholesterol O-acyltransferase in cholesterol metabolism”. Prog. Lipid Res. 18: 31—53. PMID 42927.
- ^ Taketani, S., Nishino, T. and Katsuki, H. (1979). „Characterization of sterol-ester synthetase in Saccharomyces cerevisiae”. Biochim. Biophys. Acta. 575: 148—155. PMID 389289.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Sterol+O-acyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
