Transmembranski domen ABC transportera
| Transmembranski domen ABC transportera | |
|---|---|
| Идентификатори | |
| Симбол | ABC_membrane |
| Пфам | PF00664 |
| ИнтерПро | IPR001140 |
| ПРОСИТЕ | PDOC00364 |
| СКОП | 1pf4 |
| ТЦДБ | 3.A.1 |
| ОПМ фамилија | Eksporteri lipida/lekova 1.1.10.03. Eksporteri lipida/lekova |
| ОПМ протеин | 2hyd |
Transmembranski domen ABC transportera je glavna transmembranska strukturna jedinica ATP-vezujućeg kasetnog transportera koja se sastoji od šest transmembranskih domena. Mnogi članovi ABC transporterske familije (Pfam PF00005) imaju dva takva regiona.[1][2][3][4][5][6]
Potfamilije
[уреди | уреди извор]- Sulfatni ABC transporterski permeazni protein 2 IPR005667
- Fosfatni transporterski sistem, permeazni protein 2 IPR005672
- Transporter fosfonatnog preuzimanja IPR005769
- Nitratna transportna permeaza IPR005889
- NifC-slični ABC-tip porter IPR006469
- Fosfatni ABC transporter, permeazni protein PstC IPR011864
- Molibdatni ABC transporter, permeazni protein IPR011867
- Niklov ABC transporter, permeazna podjedinica NikB IPR014156
- Niklov ABC transporter, permeazna podjedinica NikC IPR014157
- Ektoin/hidroksiektoinski ABC transporter, permeazni protein EhuD IPR014341
- Ektoin/hidroksiektoinski ABC transporter, permeazni protein EhuC IPR014342
Ljudski proteini koji sadrže ovaj domen
[уреди | уреди извор]ABCB1; ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8; ABCB9; ABCC1; ABCC10; ABCC11; ABCC12; ABCC13; ABCC2; ABCC3; ABCC4; ABCC5; ABCC6; ABCC8; ABCC9; CFTR; TAP1; TAP2; TAPL;
Reference
[уреди | уреди извор]- ^ Kerr ID (2002). „Structure and association of ATP-binding cassette transporter nucleotide-binding domains”. Biochim. Biophys. Acta. 1561 (1): 47—64. PMID 11988180. doi:10.1016/s0304-4157(01)00008-9.
- ^ Hunt JF, Yuan YR, Martsinkevich O, Millen L, Thomas PJ, Karpowich N, Dai PL, MacVey K (2001). „Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter”. Structure. 9 (7): 571—86. PMID 11470432. doi:10.1016/S0969-2126(01)00617-7.
- ^ Hunt JF, Yuan YR, Blecker S, Martsinkevich O, Millen L, Thomas PJ (2001). „The crystal structure of the MJ0796ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter”. J. Biol. Chem. 276 (34): 32313—21. PMID 11402022. doi:10.1074/jbc.M100758200.
- ^ Kim SH, Hung LW, Wang IX, Nikaido K, Liu PQ, Ames GF (1998). „Crystal structure of the ATP-binding subunit of an ABC transporter”. Nature. 396 (6712): 703—707. PMID 9872322. doi:10.1038/25393.
- ^ Welte W, Breed J, Boos W, Diederichs K, Vonrhein C, Muller C, Diez J, Greller G, Schnell C (2000). „Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis”. EMBO J. 19 (22): 5951—61. PMC 305842
. PMID 11080142. doi:10.1093/emboj/19.22.5951.
- ^ Wiley DC, Gaudet R (2001). „Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing”. EMBO J. 20 (17): 4964—72. PMC 125601 . PMID 11532960. doi:10.1093/emboj/20.17.4964.
