Липополисахарид 3-а-галактозилтрансфераза
| Lipopolisaharid 3-a-galaktoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.44 | ||||||||
| CAS broj | 9073-98-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Lipopolisaharid 3-a-galaktoziltransferaza (EC 2.4.1.44, UDP-galaktoza:lipopolisaharid alfa,3-galaktoziltransferaza, UDP-galaktoza:polisaharid galaktoziltransferaza, uridin difosfat galaktoza:lipopolisaharid alfa-3-galaktoziltransferaza, uridin difosfogalaktoza-lipopolisaharid alfa,3-galaktoziltransferaza, UDP-galaktoza:lipopolisaharid 3-alfa-D-galaktoziltransferaza) je enzim sa sistematskim imenom UDP-alfa-D-galaktoza:lipopolisaharid 3-alfa-D-galaktoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-alfa-D-galaktoza + lipopolisaharid UDP + 3-alfa-D-galaktozil-[lipopolisaharid glukoza]
Ovaj enzim prenosi alfa-D-galaktozil ostatake na D-glukozu u parcijalno završenoj srži lipopolisaharida [cf. EC 2.4.1.56 (lipopolisaharid N-acetilglukozaminultransferaza), EC 2.4.1.58 (lipopolisaharid glukoziltransferaza I) i EC 2.4.1.73 (lipopolisaharid glukoziltransferaza II)].
Reference
[уреди | уреди извор]- ^ Endo, A. & Rothfield, L. (1969). „Studies of a phospholipid-requiring bacterial enzyme. I. Purification and properties of uridine diphosphate galactose: lipopolysaccharide α-3-galactosyl transferase”. Biochemistry. 8: 3500—3507. PMID 4898284.
- ^ Wollin, R., Creeger, E.S., Rothfield, L.I., Stocker, B.A.D. and Lindberg, A.A. (1983). „Salmonella typhimurium mutants defective in UDP-D-galactose:lipopolysaccharide α-1,6-D-galactosyltransferase. Structural, immunochemical, and enzymologic studies of rfaB mutants”. J. Biol. Chem. 258: 3769—3774. PMID 6403519.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Lipopolysaccharide+3-alpha-galactosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
