Katepsin F
| Katepsin F | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.22.41 | ||||||||
| CAS broj | 65997-74-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Katepsin F (EC 3.4.22.41, Cathepsin F) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Ovaj rekombinantni enzim razlaže sintetičke supstrate sa Phe i Leu (u većoj meri nego Val) u P2, sa visokom specifičnošću slično katepsinu L
Katepsin F je lizozomalna cisteinska endopeptidaza iz familije C1 (papainske familije)
Reference
[uredi | uredi izvor]- ^ Santamaría, I., Velasco, G., Pendás, A.M., Paz, A. and López-Otín, C. (1999). „Molecular cloning and structural and functional chararcterization of cathepsin F, a new cysteine proteinase of the papain family with a long propeptide domain”. J. Biol. Chem. 274: 13800—13809. PMID 10318784.
- ^ Nägler, D.K. Sulea, T. and Ménard, R. (1999). „Full length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen”. Biochem. Biophys. Res. Commun. 257: 313—318. PMID 10198209.
- ^ Wex, T., Levy, B., Wex, H. and Brömme, D. (1999). „Human cathepsins F and W: A new subgroup of cathepsins”. Biochem. Biophys. Res. Commun. 259: 401—407. PMID 10362521.
- ^ Wang, B., Shi, G.-P., Yao, P.M., Li, Z., Chapman, H.A. and Brömme, D. (1998). „Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization”. J. Biol. Chem. 273: 32000—32008. PMID 9822672.
Literatura
[uredi | uredi izvor]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[uredi | uredi izvor]- Cathepsin+F na US National Library of Medicine Medical Subject Headings (MeSH)
