Treonin-fosfatna dekarboksilaza
| Treonin-fosfatna dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.1.81 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Treonin-fosfatna dekarboksilaza (EC 4.1.1.81, L-treonin-O-3-fosfat dekarboksilaza, CobD, L-treonin-O-3-fosfat karboksilijaza) je enzim sa sistematskim imenom L-treonin-O-3-fosfat karboksilijaza (formira (R)-1-aminopropan-2-il-fosfat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-treonin O-3-fosfat (R)-1-aminopropan-2-il fosfat + CO2
Ovaj enzim je piridoksal-fosfatni protein.
Reference
[уреди | уреди извор]- ^ Cheong, C.G., Bauer, C.B., Brushaber, K.R., Escalante-Semerena, J.C. and Rayment, I. (2002). „Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica”. Biochemistry. 41: 4798—4808. PMID 11939774.
- ^ Brushaber, K.R., O'Toole, G.A. and Escalante-Semerena, J.C. (1998). „CobD, a novel enzyme with L-threonine-O-3-phosphate decarboxylase activity, is responsible for the synthesis of (R)-1-amino-2-propanol O-2-phosphate, a proposed new intermediate in cobalamin biosynthesis in Salmonella typhimurium LT2”. J. Biol. Chem. 273: 2684—2691. PMID 9446573.
- ^ Warren, M.J., Raux, E., Schubert, H.L. and Escalante-Semerena, J.C. (2002). „The biosynthesis of adenosylcobalamin (vitamin B12)”. Nat. Prod. Rep. 19: 390—412. PMID 12195810.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Threonine-phosphate+decarboxylase на US National Library of Medicine Medical Subject Headings (MeSH)
