(RS)-1-benzil-1,2,3,4-tetrahidroizohinolin N-metiltransferaza
| (RS)-1-benzil-1,2,3,4-tetrahidroizohinolin N-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.115 | ||||||||
| CAS broj | 132084-82-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(RS)-1-benzil-1,2,3,4-tetrahidroizohinolin N-metiltransferaza (EC 2.1.1.115, norretikulinska N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:(RS)-1-benzil-1,2,3,4-tetrahidroizohinolin N-metiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + (RS)-1-benzil-1,2,3,4-tetrahidroizohinolin S-adenozil-L-homocistein + N-metil-(RS)-1-benzil-1,2,3,4-tetrahidroizohinolin
Ovaj enzim ima široku supstratnu specifičnost za (RS)-1-benzil-1,2,3,4-tetrahidroizohinoline; uključujući koklaurin, norkoklaurin, izokoklaurin, norarmepavin, noretikulin i tetrahidropapaverin.
Reference
[уреди | уреди извор]- ^ Frenzel, T., Zenk, M.H. (1990). „Purification and characterization of three isoforms of S-adenosyl-L-methionine: (R,S)-tetrahydrobenzyl-isoquinoline N-methyltransferase from Berberis koetineana cell cultures”. Phytochemistry. 29: 3491—3497.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline+N-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
