16S rRNK (guanin527-N7)-metiltransferaza
| 16S rRNK (guanin527-N7)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.170 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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16S rRNK (guanin527-N7)-metiltransferaza (EC 2.1.1.170, metiltransferaza G ribozomalne RNK male podjedinice, 16S rRNK metiltransferaza RsmG, GidB, rsmG (gen)) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (guanin527-N7)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + guanin527 u 16S rRNK S-adenozil-L-homocistein + N7-metilguanin527 u 16S rRNK
Ovaj enzim specifično metiliše guanin527 u N7 poziciju u 16S rRNK.
Reference
[уреди | уреди извор]- ^ Okamoto, S., Tamaru, A., Nakajima, C., Nishimura, K., Tanaka, Y., Tokuyama, S., Suzuki, Y. and Ochi, K. (2007). „Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria”. Mol. Microbiol. 63: 1096—1106. PMID 17238915.
- ^ Romanowski, M.J., Bonanno, J.B. and Burley, S.K. (2002). „Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold”. Proteins. 47: 563—567. PMID 12001236.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- 16S+rRNA+(guanine527-N7)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
