Indol-3-glicerol-fosfatna lijaza
| Indol-3-glicerol-fosfatna lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.2.8 | ||||||||
| CAS broj | 9014-52-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Indol-3-glicerol-fosfatna lijaza (EC 4.1.2.8, triptofan sintaza alfa, TSA, indolglicerolfosfat aldolaza, indol glicerol fosfat hidrolaza, indol sintaza, indol-3-glicerolfosfat D-gliceraldehid-3-fosfat-lijaza, indol-3-glicerol fosfat lijaza, IGL, BX1, (1S,2R)-1-C-(indol-3-il)glicerol 3-fosfat D-gliceraldehid-3-fosfat-lijaza) je enzim sa sistematskim imenom (1S,2R)-1-C-(indol-3-il)glicerol-3-fosfat D-gliceraldehid-3-fosfat-lijaza (formira indol).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1S,2R)-1-C-(indol-3-il)glicerol 3-fosfat indol + D-gliceraldehid 3-fosfat
Ovaj enzim učestvuje u odbrambenom mehanizmu protiv insekata i mikrobnih patogena u familiji trave, Graminae.
Reference
[уреди | уреди извор]- ^ Yanofsky, C. (1956). „The enzymatic conversion of anthranilic acid to indole”. J. Biol. Chem. 223: 171—184. PMID 13376586.
- ^ Frey, M., Chomet, P., Glawischnig, E., Stettner, C., Grün, S., Winklmair, A., Eisenreich, W., Bacher, A., Meeley, R.B., Briggs, S.P., Simcox, K. and Gierl, A. (1997). „Analysis of a chemical plant defense mechanism in grasses”. Science. 277: 696—699. PMID 9235894.
- ^ Frey, M., Stettner, C., Paré, P.W., Schmelz, E.A., Tumlinson, J.H. and Gierl, A. (2000). „An herbivore elicitor activates the gene for indole emission in maize”. Proc. Natl. Acad. Sci. USA. 97: 14801—14806. PMID 11106389.
- ^ Melanson, D., Chilton, M.D., Masters-Moore, D. and Chilton, W.S. (1997). „A deletion in an indole synthase gene is responsible for the DIMBOA-deficient phenotype of bxbx maize”. Proc. Natl. Acad. Sci. USA. 94: 13345—13350. PMID 9371848.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Indole-3-glycerol-phosphate+lyase на US National Library of Medicine Medical Subject Headings (MeSH)
