N-malonilurejna hidrolaza
| N-malonilurejna hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.95 | ||||||||
| CAS broj | 368888-22-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-malonilurejna hidrolaza (EC 3.5.1.95, ureidomalonaza) je enzim sa sistematskim imenom 3-okso-3-ureidopropanoat amidohidrolaza (formira ureju i malonat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim formira deo oksidativnog puta pirimidinske degradacije u pojedinim mikroorganizmima.
Reference
[uredi | uredi izvor]- ^ Soong, C.L., Ogawa, J. and Shimizu, S. (2001). „Novel amidohydrolytic reactions in oxidative pyrimidine metabolism: analysis of the barbiturase reaction and discovery of a novel enzyme, ureidomalonase”. Biochem. Biophys. Res. Commun. 286: 222—226. PMID 11485332.
- ^ Soong, C.L., Ogawa, J., Sakuradani, E. and Shimizu, S. (2002). „Barbiturase, a novel zinc-containing amidohydrolase involved in oxidative pyrimidine metabolism”. J. Biol. Chem. 277: 7051—7058. PMID 11748240.
Literatura
[uredi | uredi izvor]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[uredi | uredi izvor]- N-malonylurea+hydrolase na US National Library of Medicine Medical Subject Headings (MeSH)
