С Википедије, слободне енциклопедије
Tirozin-tRNK ligaza (EC 6.1.1.1 ) je enzim sa sistematskim imenom L-tirozin:tRNKTir ligaza (formira AMP) .[ 1] [ 2] [ 3] [ 4] [ 5] katalizuje sledeću hemijsku reakciju
ATP + L-tirozin + tRNKTyr
⇌
{\displaystyle \rightleftharpoons }
AMP + difosfat + L-tirozil-tRNKTyr
^ Allen, E.H., Glassman, E. and Schweet, R.S. (1960). „Incorporation of amino acids into ribonucleic acid. I. The role of activating enzymes” . J. Biol. Chem . 235 : 1061—1067. PMID 13792726 . ^ Cowles, J.R. & Key, J.L. (1972). „Demonstration of two tyrosyl-tRNA synthetases of pea roots”. Biochim. Biophys. Acta . 281 : 33—44. PMID 4563531 . ^ Holley, R.W., Brunngraber, E.F., Saad, F. and Williams, H.H. (1961). „Partial purification of the threonine- and tyrosine-activating enzymes from rat liver, and the effect of potassium ions on the activity of the tyrosine enzyme” . J. Biol. Chem . 236 : 197—199. PMID 13715350 . ^ Schweet, R.S. & Allen, E.H. (1958). „Purification and properties of tyrosine-activating enzyme of hog pancreas” . J. Biol. Chem . 233 : 1104—1108. PMID 13598741 . ^ Brick, P., Bhat, T.N. and Blow, D.M. (1989). „Structure of tyrosyl-tRNA synthetase refined at 2.3 Å resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate”. J. Mol. Biol . 208 : 83—98. PMID 2504923 .
6.1 : Ugljenik-kiseonik6.2 : Ugljenik-sumpor6.3 : Ugljenik-azot
