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PNQX

S Vikipedije, slobodne enciklopedije
PNQX
9-methyl-6-nitro-4,7,8,10-tetrahydro-1H-pyrido[3,4-f]quinoxaline-2,3-dione
Nazivi
IUPAC naziv
9-metil-6-nitro-4,7,8,10-tetrahidro-1H-pirido[3,4-f]hinoksalin-2,3-dion
Drugi nazivi
  • CHEMBL293206
  • SCHEMBL678318
  • BDBM50030655
  • (9S)-3-hidroksi-9-metil-6-nitro-7,8,9,10-tetrahidropirido[3,4-f]hinokslin-9-ium-2-olat
  • 9-Metil-6-nitro-1,4,7,8,9,10-heksahidro-pyrido[3,4-f]hinoksalin-2,3-dion
Identifikacija
3D model (Jmol)
  • CN1CCC2=C(C=C3C(=C2C1)NC(=O)C(=O)N3)[N+](=O)[O-]
Svojstva
C12H12N4O4
Molarna masa 276,25 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

PNQX je antagonist NMDA receptora.[3]

Reference

[uredi | uredi izvor]
  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  uredi
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ D. E. Jane; H. W. Tse; D. A. Skifter; J. M. Christie; D. T. Monaghan. Pharmacology of Ionic Channel Function: Activators and Inhibitors. Glutamate Receptor Ion Channels: Activators and Inhibitors. Pharmacology of Ionic Channel Function: Activators and Inhibitors. Springer. str. 415—478.